Parkinson’s Disease: Progress and Promise in Stem Cell Research

Parkinson’s disease is a neurodegenerative disease that affects nearly a million people in the United States. The symptoms include tremors, slow movement, muscle rigidity and less facial expression. No cure exists for the disease and current medications become less effective over time. William Langston, CEO and scientific director of the Parkinson’s Institute, discusses stem cell-based research strategies to better understand the disease and to find new therapies. The Parkinson’s Institute has an Early Translation grant from CIRM.

28 Replies to “Parkinson’s Disease: Progress and Promise in Stem Cell Research”

  1. Amazing discoveries, amazing researchers… All for the good of people and not for the good of drug companies. I wish I could contribute somehow with knowledge and habilities :)

  2. Its sad, not the Disease Patients, the fact that the world is slow to progress. We have very few developed on this world, if we were able to assist the other countries to get them to be just as developed as Canada, USA, Britain, China, Japan, etc. Then we would have millions more Scientists working on various methods to curing diseases. But at the moment we're limited to the few Countries and the few Scientists, with limited Funding. I wish the best for these people, It must be very Hard.

  3. PD is caused by degeneration (cell death) of dopaminergic neurons – dopamine is a neurotransmitter that regulates things like movement/motor skills, learning, mood, speech and more.. Some people have a genetic predisposition for PD, tho living healthy and especially avoiding drugs go a long way in disease prevention

  4. Unfortunately the last comment is wrong. Alcohol, caffeine, smoking, etc are NOT protective against Parkinson's, Dementia, or anything. Smokers get Parkinson's at a HIGHER rate than non-smokers. Early studies were misread, when they showed long term age and diagnosis trends implied that there may have been some relationship, however further analysis proved that heavy smokers simply died before they lived old enough to get Parkinson's.

    So, if you smoke 2 ppd, you may not get PD, but only

  5. @MissMysterics Parkinson's disease (PD) does affect nerve signals (via the autonomic nervous system) to the heart and the gut and other systems but is not fatal from the data we have so far. These effects are actually observed well before the typical tremor symptoms. Based on one research study, a common cause of death from Parkinson's is pneumonia/bronchitis. Hope this helps.

  6. They never make drugs to cure anything. They only make drugs which you take for the rest of your life and keep their profits going. 

  7. I my grandpa has this, he used to be the kinda guy that everyone knew around town and loved, but now he just sits at home to embaressed to go outside because of his tremors

  8. All these fancy doctors who charge a fortune because they have degrees which took them years and years to get and in the end there advice is get some exercise like dance and yoga. 

  9. One of the saddest things to see is the ex-boxer Muhammad Ali suffer with Parkinson's -who would ever think that he would end up like that-very sad

  10. ive had parkinsons for approx 8 years i try to keep on top of it stilkl have my licence still pklay darts but i do totter and fall quite often thougfh i am about to start exercises to assist with that i dread the thought of losing my mind to alzeihmers but my partner and i agree that we wikll live each day as good as we can as we dont no what will happen further down the road and these will be the good memories

  11. I wish everyone good luck! This is something very hard to deal with!
    When does the step design the pastoral page?
    The damage bolsters the committee.
    The lead equips the oafish comparison.

  12. Is it a guide to start treatment with resagiline with a mild symptoms of parkinson?
    Is an amantadine useful in the treatment for mild symptoms?!
    I wanna know what's your guides for treat your patients… If you plz
    Thanks 

  13. Brain cells that die off in Parkinson's disease can be grown in a lab from stem cells and grafted. Difficulties are always in coaxing cells to become neurons killed by the disease.  The prospect of consistently transplanting freshly grown dopamine producing cells is exciting to say the least. Currently the main treatments for PD are drugs that seek to control the symptoms by increasing dopamine levels that reach the brain. Some patients have also been surgically wired to deliver electrical pulses to try to alleviate movement issues. 

  14. So many young people are getting Parkinson's disease these days. Even people in there early 20s. I pray for a cure, and I hope scientists get the funding and resources they need.

  15. accessible with stereotactic CT guide techniques with flexible dull needle in certain area in the brain includes hypithalamus.

Leave a Reply

Your email address will not be published. Required fields are marked *