Alzheimer's: more research on medicinal cannabis

Alzheimer's disease is not curable until now. A report from the United States indicates that the pharmaceutical industry has made considerable efforts to provide affected people with options for drugs to improve their quality of life. In fact, there are now four FDA-approved drugs to treat memory loss related to Alzheimer's disease. However, the efficiency rates are low.

Various studies suggest that medicinal cannabis could be effective in neurodegenerative diseases such as Alzheimer's disease. This is also confirmed by Seattle-based neuroscientist Dr. Ethan Russo, director of research and development at the International Cannabis and Cannabinoids Institute. Russo's focus is on the causes of the disease as well as treatment with cannabis-based drugs. According to Russo, the effect of entourage, that is to say the effect of all the ingredients of cannabis, is particularly important.

"All the components of the cannabis plant work together as a symphony.You can consider THC as a soloist with a significant amount of CBD, but you also have these other components that create a harmony that really adds to the overall effect ", says Russo.

Meaning of Entourage effect

As early as 2011, Russo published the results of his study on phytocannabinoid synergies and explained the interactions between cannabis compounds.

The importance of this effect of entourage can not be emphasized enough, according to Russo, especially in the current hype of the CBD. The report also states that Martha Stewart's recent entrepreneurial gambling on the CBD pet scene has been perceived by many people and by the media as a creator of credibility for the cannabis industry (Leafly report). .of). But CBD without THC is much less effective based on empirical research studies, Russo said.

Alzheimer: clinical trials are needed

Russo says it's time to conduct clinical trials. It has been shown that THC and CBD interfere with the production of abnormal toxic substances in the brain of Alzheimer's disease.

"THC and CBD are known neuroprotective agents that can potentially slow down or even stop the degenerative process," says Russo.

In addition, the role of the endocannabinoid system in neurodegenerative diseases such as Alzheimer's disease has been studied in several studies. For example, researchers have discovered changes in the endocannabinoid system in deceased Alzheimer's patients, particularly the main cells of the central nervous system of the immune system. For this reason, it is thought that the endocannabinoid system, which can be activated by cannabis-based drugs, is important for the development of Alzheimer's disease.

The results of previous research are promising. However, intensive research is needed to clarify exactly how medicinal cannabis can work in neurodegenerative diseases.

Other interesting articles:
Cannabis as a treatment option in neurodegenerative diseases
Endocannabinoids prolong the life of worms
Effect of cannabigerol (CBG) – a cannabinoid with potential

Note: In this article, we report the prescription of CBD or even cannabidiol. This article makes no suggestion for a possible goal. The benefits are left to pharmacists.