New Migraine Headache Relief – How Long Should We Wait For A Miracle?

Will this new miracle migraine medicine ever see the light of day? For migraine patients there is real hope for a new treatment. The person behind this discovery is professor Lars Edvinsson, at the University Hospital in Lund, south Sweden, that discovered this peptide, called CGRP, in 1984. This drug was slated for release on the market 2010. So, what was the reason for this not to take place?

For about two years time we have now seen in the magazines and on the internet about the new "miracle medicine" Telcagepant. So what was the great news about this drug in the first place? Absolutely no side effects! Wasn't that just a dream for all us migraine sufferers all over the world? Unfortunately, that dream did not last longer than a year.

Just suddenly the American drug company Merck, that developed the medicine, withdrew the introduction of this drug. And the hope for the migraine patients dropped very quickly. Soon we understood that it was the FDA, Food and Drug Administration, in USA, that did not approve of the introduction of this Telcagepant drug. Later on we heard that it was Merck themselves who stopped the introduction and informed the FDA about it. So what now? Is the hope gone for all those patients that are waiting for their new migraine headache relief medicine?

It was said that the medicine should have no side effects whatever. That was a very nice thought, but everyone with just a little understanding of how medicines work inside the body knows that this is almost impossible. But, the main reason for stopping the introduction was most likely side effects on the liver. Apart from that they found nausea, fatigue, dizziness and dry mouth. Those are very common side effects for many medicines and could not have been the main reason for rejecting the drug. So most likely it was the liver problem that made Merck and the FDA stop the introduction.

Now the introduction will take place in autumn 2011 in spite of the fact that the liver problem has not yet been solved. But I guess that the FDA allows Merck one year to get the side effects under control. One year, in this case, is a lot of time to get things working and hopefully get rid of that liver ghost. So there is still hope for this new migraine headache relief medicine. But one year is a long time to wait for many migraine patients.

Passive Smoking: Long Term Effects

Passive smoking may not directly cause certain diseases related to smoking, but it gives you a chance of developing anything smoking-related, at a higher rate. Studies have shown and confirmed an increased risk in the following:

In infancy and children:

o birth defects

o sudden infant death syndrome (SIDS)

o low birthweight

o illnesses in children

o middle ear infection

o learning difficulty

o behavior problems (ie depression, anxiety and immaturity)

o allergies

o asthma (induction & aggravation)

o bronchitis (induction & aggravation)

o pneumonia (induction & aggravation)

o Meningococcal infections in children

o Cancers and leukaemia in children

In adults:

o heart disease

o stroke

o lung cancer

o nasal cancer

o spontaneous abortion (miscarriage)

o asthma exacerbation in adults

o cystic fibrosis (exacerbation)

o reduced lung function

o cervical cancer

o infections

o ear infections

o chronic obstructive pulmonary disease

o bronchitis

o allergies and death of children

o aggravation of asthma, allergies, and other conditions

Passive Smoking and Lung Cancer

Non-smokers have a twenty-five percent increased risk of lung cancer when exposed to passive smoking in the home. In a press release by the World Health Organization (WHO) on March 9, 1998, it said that the increased risk of lung cancer among non-smoking spouses of smokers was estimated at sixteen percent and in the workplace, an estimated increased risk of seventeen percent. In 2002, the International Agency for Research on Cancer (IARC) of the WHO, a group of 29 experts from 12 countries, convened by the Monographs Program. They reviewed all major published evidence related to tobacco smoking and cancer.

Their conclusion:

These meta-analyzes show that there is a statistically significant and consistent association between lung cancer risk in spouses of smokers and exposure to secondhand tobacco smoke from the minority who smokes. The excess risk is of the order of 20% for women and 30% for men and remains after controlling for some potential sources of bias and confounding.

Passive Smoking and other Cancers

Conventional studies tend to focus on finding the health effects of ETS on the respiratory system. Newer studies have found associations between passive smoking and cervical, bladder, nasal-sinus, and brain cancer.

Among active smokers, there is recorded a risk of cancer to:

o the renal pelvis (part of the ureter that receives urine from the kidney)

o possibly the renal adenocarcinoma (the glands of the kidney)

o parts of the mouth and throat such as the lip, oropharynx (the back of the mouth), larynx (voice box), and hypopharynx (area below the pharynx or throat)

o the esophageal (tube from the pharynx to the stomach)

o stomach, liver and pancreas.

Passive Smoking and Heart Disease

In the early 1990s, studies by Glantz and Parmley estimated that the third leading preventable cause of death in the United States was heart disease. The first two were active smoking and alcohol abuse. It was also found out that non-smokers living with smokers had an increased risk of heart disease of around 30%.

An examination of a large sample in the United States also showed an elevated heart disease risk of around 20%. Knowing how pervasive heart disease is among non-smokers in the United States, a 20% additional risk is very significant.

From then on, researchers have proven conclusively that there is not just an increased risk of heart disease but that the risks are non-linear. The increased risks and effects on the heart are similar to that of lung cancer where the risk is almost in proportion to the exposure. In passive smoking, the risk of heart disease may be half that of someone smoking 20 cigarettes a day even though that person is only inhaling 1% of the smoke. New studies reveal that exposure to ETS also causes platelet aggregation, a condition where the blood starts to thicken, and a narrowing of arteries and blood flow reduction when endothelial cells dysfunction.

Passive smoking kills an estimated 53,000 non-smokers per year. It is the 3rd leading cause of preventable death in the US

How Long Do The Effects Of Ice Last?

The effects usually last for between four and 12 hours, although methamphetamine can be detected in blood and urine for up to 72 hours.
This means that it takes 12 34 hours for the ice half life & how long effects last. How long does ice stay in your system and urine? Short term, term & side effects. Swim told me that meth’s euphoria doesn’t last 12 hours, but rather only about 3 4 hours sometimes less. Crystal methamphetamine works by stimulating the central nervous system and produces effects of’rush’ euphoria. To 50 percent of a dose meth can exit the body exactly as it came in that is to say, not metabolized or processed at all, with user experiencing no stimulant effects chronic methamphetamine use severely impact both and mind. Swim definitely felt speedy for at least 12 hours, but needs to re dose after about 3 hours in order get back 22 mar 2015 ice facts what is it, how it affects you and used. How long does meth last? Addiction blog drug. When the ice wears off, person is likely to be 19 feb 2017 effects usually last for between four and 12 hours, although methamphetamine can detected in blood urine up 72 hours 4 mar 2016 we’ll explore how drug affects body long those last, as some other important information about. Dilated pupils, decreased fatigue, ect 11 aug 2008 the media constantly stresses long lasting nature of meth. We should note that the first kick depends mainly on way of administration. Taking ice for the first time; Advice and tips [archive] bluelight. In most cases, the high from ice methamphetamine lasts much longer than cocaine. So instead i am getting one point of ice. Meth comedown withdrawal & symptoms. Smoking meth side effects and dangers rehabs. It has a plasma half life of 12 34 hours. How long does ice last when you snort it? Youtube. Googleusercontent search. Short term effects of smoking crystal meth what does using make you feel like? Drug free how long side stay with you? Kci. Your dose at last use. What is ice? How ice used, risks of how long does meth stay in your system? . The effects of meth last for around 8 24 hours, depending on how much is taken, well the kidneys and liver function, individual user’s body chemistry. How long does meth last? Addiction blogdrug abuse effects of ice narconon. When people inject ice, the peak blood concentrations happen shortly after intake. 6) meth how long does the side effects of meth stay with you ex. Normally i would go with pills or speed, but the are shit and can’t get speed. But what is this insidious drug and are impacts of its long term use? Ice a stimulant drug, which means it speeds up the messages travelling between brain body as fast acting stimulant, meth does not stay in system for very. I was wondering 1) how long are effects expected to last if smoked? 2) what is a good starting dose for smoking? The. How long does crystal meth stay in your system? . Other desired effects of crystal meth include an intense, initial ‘rush’ that may persist for 30 minutes.

The Long Wait Before You Fall Pregnant

You and your partner have decided that you want to start a family. That moment is very exciting and you literally cannot wait for the day when the baby is born. But the reality is, of course, that it is going to take nine months before a baby is born and the time before conception could be months. What are you to do before that time comes?

In short, take action and be patient. Firstly, visit your gynaecologist to advise you how long the contraception you’re on will wear off once you stop taking it. When you stop taking the contraception pill you could fall pregnant almost immediately. Of course this does differ from woman to woman as some take about month or longer. With the Mirena you could fall pregnant after a month.

If you don’t experience regular periods, you will have to get this checked. However, if your gynaecologist confirms that your reproductive system is healthy then it’s best not to be worried. It may take you a bit longer to conceive because your cycle is irregular, but just because it is irregular doesn’t mean that you’re not ovulating. Your body may work differently to someone else’s and there’s nothing wrong with that. It just means that you will need to be a bit more patient.

In the meantime it is a good idea to look after your body and your general health. You need to prepare your body to host a new human being so make sure that you are getting all the nutrition possible to give that little human being a good start in life. Start with taking folic acid supplements daily and eat your fruit and vegetables. You could also take a multi-vitamin at this stage if you are not able to get all the nutrients you need. Avoid alcoholic drinks and any unnecessary medications. Stop smoking. Cut down on your caffeine intake and drink a lot of water to keep your body hydrated. Enjoy light exercises but avoid heavy or excessive exercises.

After a year of trying to conceive and nothing has happened, it is advisable to go to a fertility clinic. The fertility doctor will run a number of tests to determine what the cause of infertility could be. Once it has been diagnosed, you can venture forward with the plan of action recommended by the fertility doctor.

Whatever your plan of action when it comes to trying to fall pregnant, it is important to remain calm and avoid stress. It can happen at any time.

The History of Obesity – How Long Has America Faced This Problem?

It’s obvious that obesity is a problem facing the United States, but when did it become seen as an epidemic? It’s not obesity that actually causes deaths, but is a cause of the many diseases that do: diabetes mellitus and vascular disease, for example. Medicare, however, announced obesity a disease in 2004, and as a result, we have access to many treatments, including diets, surgery, exercise programs and psychotherapy. We’ve really been thinking about obesity an epidemic much earlier than the year 2004, and we now talk about obesity as a global epidemic in many countries, including the US, the UK, Canada, Australia, and China. We think of obesity as the major public health problem of the twenty-first Century.

Some argue that we are panicking about obesity in a moral sense, not simply a wellness sense, whereas obesity is a condition that threatens our social values and norms. We’ve been defining it as a national problem, not an individual health problem. We are concerned about the implications on us as a society. Despite the fact that we’ve been concerned about obesity for a very long time, it wasn’t until the 1980s that obesity as an epidemic was identified for Americans. From the 1990s on, society has been on a quest to ascertain causes of obesity related to diesase; in 1997, researchers thought that obesity could be caused by a virus that mimics AIDS in the manner in which it spreads. In 2007, another group theorized that obesity might be caused by what they called a “social infection,” meaning that obese family and friends influence individuals to overeat, causing obesity.

Our social worry over obesity isn’t new. In literature, authors like Charles Dickens write about character types whose considerable physical characteristics represent stupidity, laziness, and general moral lacking. In the 1930s and 40s, doctors found a pituitary tumor in a young boy, and linked it directly to his obesity. We were obsessed with attempts to find specific causes for obesity because we were so afraid of it. Suddenly, obesity became inextricably connected to physical disease.

Obese people have long felt stigmatized by their weight. In Shakespeare, his character Falstaff searched for a cure for his weight because of his anxiety over it. Nineteenth-century doctors actually labeled Jews the “diabetic race,” supposedly because of their likelihood to overindulge. In the 1950s, a German-Jewish doctor named Hilde Bruch theorized that obesity truly sprang from family dysfunction and bad mothering.

Today, doctors point to American fast food and global financial progress as the cause of obesity instead of nodding toward racial causes. Perhaps obesity and its treatments are simply part of a system of modernization. We are obsessed with global health, leading to our anxiety about the obesity epidemic. Truly, it’s not bad to be worried about obesity numbers in the world; the number of obese people in this country is steadily climbing. We know that obesity leads to other, more inherently dangerous illnesses, ranging from diabetes to heart disease. Obesity, then, really does kill, albeit indirectly. There have always been obese people, just not so many. Now, the question is how to help them.